12mm. Radionuclide scan, technetium pyrophosphate scan is pathognomic scans for amyloidosis that are pocket friendly and easily available in various hospitals. Certain biomarkers such as Pro-BNP and Ca-125 will be raised. It has been observed that elderly people get afflicted by ATTR-CM as compared to youngsters. Three percent of population above the age of sixty-five years have amyloid deposition and fifteen per cent above the age of eighty-five years. Dr. Nitin Burkule said that the awareness about the disease among healthcare professionals has gone up. Dr. Chopra exclaimed that this disease is a great mimic. He stated - "Conditions like high blood pressure, age related changes, hypertrophic cardiomyopathy present with similar changes. Certain typical features may be present in their entirety or in a subtle form. So, the focus should be to pick up those changes. If a person with high blood pressure suddenly finds that hypertension is not present anymore, it may indicate towards amyloidosis. Even though it is not the case for everyone but can happen." Once patients present with symptoms and a diagnosis is made, the prognosis is poor. With ATTR-CM, doctors focus on easing heart failure symptoms and slowing or stopping the formation of amyloid deposits. Certain drugs known as transthyretin stabilizers are available for the management of the disease preventing formation of new proteins but not remove the already present fibers. If the individual is not responding to usual treatment, then heart transplant is the only option. Scintigraphy is a test that uses a substance called a tracer and a scanning machine to create detailed images of the heart. If the tracer finds amyloid proteins in the heart, it will bind to them and light up on the pictures of your heart like a "heat map with a hot spot." Complications of the ATTR-CM include: - Shortness of breath - Low flow low gradient aortic stenosis - Swelling in the feet, ankles, and legs - Palpitations - ventricular ectopics or abnormal heart rhythms - Inability to respond to standard medications - Sudden cardiac arrest from which they have been revived - Heart Failure As this is a rare disease, patients must be alert about the symptoms and should talk to their health care providers about management options. Early diagnosis is critical. If a family member has been diagnosed with ATTR-CM, the first-degree relatives should be screened as early as possible. (1) Source - Article published in the Medical Journal, Armed Forces of India titled Cardiovascular disease in India: A 360 degree overview, This is an IHW Council awareness initiative supported by Pfizer. Please consult your doctor for guidance on the information stated herein or further information on the subject. The content herein is meant for informational and awareness purposes only and should not be construed as a substitute for medical advice. The views expressed herein by the author are their own independent views and Pfizer may not necessarily endorse the same. While due care and caution has been taken to ensure that the content is free from mistakes or omissions, Pfizer makes no representations or warranties of any kind, expressed or implied, as to the accuracy, completeness or adequacy of the contents herein and will not be liable for any damages, adverse events, and personal liability arising therefrom. This story has been provided by Mediawire. ANI will not be responsible in any way for the content in this article. (ANI/Mediawire)"/>

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