(Photo credit: Kyle Ross-Imagn Images)

Andrew Painter struck out eight in 5 1/3 innings in his major league debut as the Philadelphia Phillies topped the visiting Washington Nationals 3-2 on Tuesday.

The Phillies' top pitching prospect, Painter (1-0) allowed one run, four hits and a walk against a Nationals team that entered the game tied for the major league lead in runs scored. Kyle Schwarber and Adolis Garcia homered for the Phillies, who had lost three of their first four games.

Daylen Lile had three hits for Washington, which had won three of its first four contests. James Wood came up with the tying run on second and two outs in the ninth, but Brandon Marsh tracked down his liner to deep left for the final out.

Philadelphia scored a run in the third, fourth and fifth innings against Zack Littell (0-1) to stake Painter to a 3-0 lead. Jhoan Duran worked the ninth for his second save.

Giants 9, Padres 3

Willy Adames led off the game with a homer and finished with a career-high-tying four hits to go with two RBIs and San Francisco's offense finally exploded during a victory over host San Diego.

Jung Hoo Lee had three hits and three RBIs, and Matt Chapman (solo homer) and Rafeal Devers had two hits apiece as the Giants racked up 16 hits. Heliot Ramos drove in two runs for the Giants, who went 6-for-12 with runners in scoring position while beating San Diego for the second straight night. Giants starter Logan Webb (1-1) gave up three runs and three hits over six innings.

Jackson Merrill and Miguel Andujar had RBI hits for the Padres, who have lost four of five games to start the season. German Marquez (0-1) struggled in his San Diego debut, serving up two homers while pitching just three innings. He gave up four runs and eight hits.

Yankees 5, Mariners 0

Max Fried pitched seven innings of three-hit ball as New York blanked host Seattle, their third shutout win in five games this season.

Giancarlo Stanton went 2-for-4 with a double and two RBIs as the Yankees evened the three-game series at one victory apiece. New York's Trent Grisham, Cody Bellinger and Ben Rice each had two hits. Fried (2-0) walked one and struck out six.

Seattle's Josh Naylor lined a single to center with two outs in the fourth inning. It was Naylor's first hit of the season, breaking an 0-for-20 slump. The Mariners' only other hits off Fried came in the seventh, an infield single by Julio Rodriguez and a two-out liner to right by Brendan Donovan. Logan Gilbert (0-1) allowed five runs on seven hits over 5 1/3 innings.

Dodgers 4, Guardians 1

Shohei Ohtani gave up one hit over six scoreless innings in his season pitching debut and Max Muncy hit a home run as Los Angeles earned a victory over visiting Cleveland.

Andy Pages collected two hits and two RBIs and Teoscar Hernandez drove in his first run of the season. Ohtani (1-0), who was placed in the No. 5 spot of the rotation to start the season as the Dodgers look to manage his pitching workload, walked three batters and struck out six.

Guardians right-hander Tanner Bibee (0-1) gave up one run on four hits over four innings after his start was in doubt because of shoulder inflammation that developed during his Opening Day outing at Seattle. Brayan Rocchio broke up the Dodgers' shutout bid with an RBI single in the ninth.

Cardinals 3, Mets 0

Andre Pallante and a quartet of relievers combined on a three-hit shutout for host St. Louis, which beat New York in the middle game of a three-game series.

Ivan Herrera had a two-run double in the third and Ramon Urias added a homer leading off the seventh for the Cardinals, who recorded their first shutout since last Sept. 16. Pallante (1-0) gave up all three hits over five-plus innings.

Kodai Senga took the hard-luck loss after whiffing nine over six innings. The Mets were blanked for the first time since a 4-0 loss to the Miami Marlins in the season finale last Sept. 28 -- a defeat that eliminated New York from playoff contention.

Rangers 8, Orioles 5

Danny Jansen hit a three-run homer for one of his three hits as Texas beat host Baltimore.

Ezequiel Duran and Corey Seager also homered for the Rangers, who have won four in a row. Rangers starter Jacob deGrom was strong through three innings, but he was charged with three runs on six hits in 4 2/3 innings in his rescheduled start. Neck stiffness delayed his season debut from the weekend.

Pete Alonso, the Orioles' highly acclaimed free-agent signee, smacked his first home run with his new team. Taylor Ward had four hits from Baltimore's leadoff position, and he and Gunnar Henderson each produced a two-run double.

Pirates 8, Reds 3

Oneil Cruz hit a pair of home runs and Ryan O'Hearn and Bryan Reynolds hit back-to-back home runs as Pittsburgh's offense broke out during a win over host Cincinnati.

O'Hearn and Reynolds' successive homers highlighted a five-run second inning. Cruz smacked a towering 444-foot blast in the fourth inning, and later added a two-run homer in the ninth to pad Pittsburgh's lead after Cincinnati cut it to 6-3 in the bottom of the eighth.

Pirates rookie Bubba Chandler didn't allow a hit but issued six walks through 4 1/3 innings. The Reds were held to one hit through seven innings before Elly De La Cruz and Sal Stewart opened the eighth with back-to-back home runs.

Angels 2, Cubs 0

Jose Soriano allowed two hits over six shutout innings and Logan O'Hoppe hit a two-out, two-run single in the sixth inning as Los Angeles won at Chicago.

Relievers Chase Silseth, Drew Pomeranz and Jordan Romano followed Soriano to complete a four-hit shutout. Romano got the last two outs for his second save.

Cubs starter Jameson Taillon tossed 4 2/3 scoreless innings. Ian Happ saw his three-game homer streak come to an end, as he went 0-for-2 with two walks.

Astros 9, Red Sox 2

Hunter Brown allowed one run and struck out eight in six innings to help Houston stretch its winning streak to four games by beating visiting Boston.

The only hit Brown (1-0) allowed was a Connor Wong RBI double in the fifth. Cody Bolton struck out five over the final three innings to earn his first career save.

Yordan Alvarez and Cam Smith each hit solo home runs for the Astros. Alvarez, Christian Walker and Carlos Correa each had two hits and two RBIs in the win. Ceddanne Rafaela homered for the Red Sox. Brayan Bello (0-1) yielded six runs (five earned) in 4 2/3 innings.

Marlins 9, White Sox 2

Griffin Conine, Liam Hicks and Owen Caissie drove in two runs apiece as host Miami defeated Chicago.

After Janson Junk's 4 1/3-inning start, four relievers -- Andrew Nardi, Anthony Bender (1-0), Calvin Faucher and Pete Fairbanks -- combined to deal eight strikeouts and hold Miami hitless over the final 4 2/3 frames.

Erick Fedde (0-1) took the loss, allowing six hits, one walk and four runs (three earned) in five innings. The White Sox, who are coming off three straight 100-loss seasons, made three errors, all on throws to the plate. Two of the miscues were charged to center fielder Luisangel Acuna.

Athletics 5, Braves 2

Andy Ibanez and Jacob Wilson both drove in their first two runs of the season to help the Athletics earn their first victory of the year over host Atlanta.

Ibanez went 2-for-4, scored a run and drove in two. Wilson was 2-for-4 with a double and two RBIs. A's starter Aaron Civale (1-0), signed as a free agent in the offseason, worked five innings and allowed two runs on four hits and one walk, striking out three.

Drake Baldwin hit his third homer of the season to lead the Braves.

Blue Jays 5, Rockies 1

Max Scherzer pitched six effective innings in the 41-year-old's season debut and Toronto defeated visiting Colorado.

Scherzer (1-0) allowed one run, four hits and one walk while striking out four in six innings. Jesus Sanchez, Vladimir Guerrero Jr. and Nathan Lukes each had two hits and an RBI to help Toronto split the opening two games of the three-game series. It was the fourth win in five games for Toronto, while Colorado has dropped four of five.

Hunter Goodman hit a solo home run for the Rockies. TJ Rumfield added three hits. Colorado starter Ryan Feltner retired his first eight batters before Andres Gimenez lined an infield single off his right hip with two outs in the third. Feltner finished the inning with a walk and groundout but did not return for the fourth because of a contusion in the hip area. He allowed no runs, one hit and one walk with four strikeouts in three innings.

Brewers 6, Rays 2

Gary Sanchez and Jake Bauers homered and Brandon Woodruff pitched five effective innings in his season debut, pacing Milwaukee past visiting Tampa Bay.

The result spoiled the first appearance for Tampa Bay starter Shane McClanahan in 972 days. McClanahan, who was back on a major league mound for the first time since Aug. 2, 2023, allowed three runs, two earned, on two hits in 4 2/3 innings. He struck out four and walked three in a 79-pitch outing.

Woodruff (1-0), who sustained a season-ending lat injury in late September that kept him out of the playoffs, allowed two solo homers and four hits while striking out six without a walk. Woodruff also missed all of 2024 following shoulder surgery.

--Field Level Media